- Overview
- Product Description
- Product Details
- Application&Function
- Specification
Basic Info.
Model NO.
D-sung Astragaloside
Product Name
Astragaloside
Name
Astragaloside Powder
Appearance
Brown Powder
Color
Brown
Grade
Pharmaceutical Grade
Assay
HPLC 99%
Application
Veterinary
Specific
COA
Test Method
HPLC
Shelf Life
2 Years
CAS No.
83207-58-3
Mf
C41h68o14
MW
784.97000
Boiling Point
895.7ºC at 760 Mmhg
Density
1.39 g/cm3
Transport Package
Negotiable
Specification
99%
Trademark
D-sung
Origin
Shaanxi Xi′an
Production Capacity
500kg/Month
Product Description
Natural CAS 83207-58-3 Astragaloside Astragalus Extract Astragaloside IV Anti-Aging Astragaloside 
| Product name | Astragaloside |
| Cas number | 83207-58-3 |
| Appearance | Brown powder |
| MF | C41H68O14 |
| MW | 784.97000 |
Astragaloside IV is an organic compound with the chemical formula C41H68O14. It is a white crystalline powder and is extracted from Astragalus membranaceus. The main active ingredients in Astragalus membranaceus are Astragalus polysaccharides, Astragalus saponins, and Astragalus isoflavones. Astragaloside IV is mainly used as the standard for evaluating the quality of Astragalus membranaceus. Pharmacological studies have shown that Astragalus membranaceus has effects such as enhancing the body's immune function, strengthening the heart and lowering blood pressure, lowering blood sugar, diuresis, anti-aging, and anti-fatigue 
The main effective ingredients in Astragalus membranaceus are polysaccharides and astragalosides. Astragaloside is divided into Astragaloside I, Astragaloside II, and Astragaloside IV. Among them, astragaloside IV, or astragaloside IV, has the best biological activity. Astragaloside IV not only has the effects of Astragalus polysaccharides, but also has some incomparable effects compared to Astragalus polysaccharides. Its pharmacological intensity is more than twice that of conventional Astragalus polysaccharides, and its antiviral effect is 30 times that of Astragalus polysaccharides. Due to its low content and good effect, it is also known as "super astragalus polysaccharides".
Pharmacological effects of astragaloside IV
1. Enhance the body's immune system and enhance its disease resistance.
It can specifically and non-specific exclude foreign objects that invade the body, promote specific, immune, and non-specific immunity, and improve the body's disease resistance. It can promote the generation of antibodies in the body and significantly enhance the number of antibody forming cells and hemolytic test values. Astragaloside IV can significantly improve the lymphocyte transformation level and E rosette formation rate of coccidia immunized chickens, and is an effective activator of the monocyte macrophage system. Astragaloside IV can also enhance oxidation, increase GSH-PX and SOD activities in immune organs, and enhance immune defense and monitoring functions.
2. Antiviral effects.
Its antiviral principle is to stimulate the function of macrophages and T cells, increase the number of E-ring forming cells, induce cytokines, promote the induction of interleukin, and produce endogenous interferon in the animal body, thus achieving the goal of antiviral therapy. The experiment has shown that the total protection rate of astragaloside IV on IBD can reach 98.33%, which can effectively prevent and treat IBD. There is no significant difference in the prevention and treatment effect compared to high immunity egg yolk solution. Astragaloside IV can enhance the function of antioxidant enzyme system in the body, reduce the content of LP0, and reduce the damage of reactive oxygen free radicals to the body, thus reducing the incidence rate and mortality of MD. It can improve immune dysfunction caused by tumors in the body, promote immune cell activation and release endogenous factors, and prevent peroxidation from killing and inhibiting tumor cells; Astragaloside IV has the effect of inhibiting the growth of influenza virus and the activity of sialidase, and has a significant effect on the function of influenza virus cell membrane and the adsorption and penetration of sensitive cells by the virus. The mortality rate and egg production rate of birds were greatly reduced, and the egg production rate and shell quality were significantly improved compared with the control group only using amantadine, and the effect of astragalus polysaccharide was not obvious; Astragaloside IV has a strong killing and inhibitory effect on ND virus. The premise is that the use of astragaloside A is prior to the discovery of infection with ND virus, so it is best to use astragaloside A for a long time. Three day old AA broilers with avian myeloblastic leukemia (AMB) are infected with the virus of AMB and given astragaloside A at the same time, which can reduce the incidence rate and mortality of AMB, increase the content of LPO in immune organs such as spleen and thymus, and significantly enhance the scavenging effect of immune organs such as spleen and thymus on myelogenous tumor cells; Secondly, astragaloside IV also has significant preventive and therapeutic effects on respiratory diseases such as infectious laryngotracheitis in chickens.
3. Anti stress effects.
Astragaloside IV can prevent adrenal hyperplasia and thymic atrophy during the stress response warning period, prevent abnormal changes during the stress response resistance and failure period, and thus play an anti stress role, especially in the bidirectional regulation of enzymes during nutrient metabolism, which to some extent alleviates and eliminates the impact of heat stress on physiological functions of the body.
4. As a growth promoting agent.
It can enhance the physiological metabolism of cells, promote blood circulation, enhance the metabolism of animal bodies, and play a nutritional and health role. Research has shown that it can promote the growth of bifidobacteria and lactic acid bacteria, and has the effect of probiotics.
5. Astragaloside IV can improve cardiovascular function.
Strengthen cardiac contractility, protect myocardium, and combat heart failure. It also has liver protection, anti-inflammatory, analgesic and other effects. It can be used as an adjuvant therapy for various viral and bacterial diseases.
The main effective ingredients in Astragalus membranaceus are polysaccharides and astragalosides. Astragaloside is divided into Astragaloside I, Astragaloside II, and Astragaloside IV. Among them, astragaloside IV, or astragaloside IV, has the best biological activity. Astragaloside IV not only has the effects of Astragalus polysaccharides, but also has some incomparable effects compared to Astragalus polysaccharides. Its pharmacological intensity is more than twice that of conventional Astragalus polysaccharides, and its antiviral effect is 30 times that of Astragalus polysaccharides. Due to its low content and good effect, it is also known as "super astragalus polysaccharides".Pharmacological effects of astragaloside IV
1. Enhance the body's immune system and enhance its disease resistance.
It can specifically and non-specific exclude foreign objects that invade the body, promote specific, immune, and non-specific immunity, and improve the body's disease resistance. It can promote the generation of antibodies in the body and significantly enhance the number of antibody forming cells and hemolytic test values. Astragaloside IV can significantly improve the lymphocyte transformation level and E rosette formation rate of coccidia immunized chickens, and is an effective activator of the monocyte macrophage system. Astragaloside IV can also enhance oxidation, increase GSH-PX and SOD activities in immune organs, and enhance immune defense and monitoring functions.
2. Antiviral effects.
Its antiviral principle is to stimulate the function of macrophages and T cells, increase the number of E-ring forming cells, induce cytokines, promote the induction of interleukin, and produce endogenous interferon in the animal body, thus achieving the goal of antiviral therapy. The experiment has shown that the total protection rate of astragaloside IV on IBD can reach 98.33%, which can effectively prevent and treat IBD. There is no significant difference in the prevention and treatment effect compared to high immunity egg yolk solution. Astragaloside IV can enhance the function of antioxidant enzyme system in the body, reduce the content of LP0, and reduce the damage of reactive oxygen free radicals to the body, thus reducing the incidence rate and mortality of MD. It can improve immune dysfunction caused by tumors in the body, promote immune cell activation and release endogenous factors, and prevent peroxidation from killing and inhibiting tumor cells; Astragaloside IV has the effect of inhibiting the growth of influenza virus and the activity of sialidase, and has a significant effect on the function of influenza virus cell membrane and the adsorption and penetration of sensitive cells by the virus. The mortality rate and egg production rate of birds were greatly reduced, and the egg production rate and shell quality were significantly improved compared with the control group only using amantadine, and the effect of astragalus polysaccharide was not obvious; Astragaloside IV has a strong killing and inhibitory effect on ND virus. The premise is that the use of astragaloside A is prior to the discovery of infection with ND virus, so it is best to use astragaloside A for a long time. Three day old AA broilers with avian myeloblastic leukemia (AMB) are infected with the virus of AMB and given astragaloside A at the same time, which can reduce the incidence rate and mortality of AMB, increase the content of LPO in immune organs such as spleen and thymus, and significantly enhance the scavenging effect of immune organs such as spleen and thymus on myelogenous tumor cells; Secondly, astragaloside IV also has significant preventive and therapeutic effects on respiratory diseases such as infectious laryngotracheitis in chickens.
3. Anti stress effects.
Astragaloside IV can prevent adrenal hyperplasia and thymic atrophy during the stress response warning period, prevent abnormal changes during the stress response resistance and failure period, and thus play an anti stress role, especially in the bidirectional regulation of enzymes during nutrient metabolism, which to some extent alleviates and eliminates the impact of heat stress on physiological functions of the body.
4. As a growth promoting agent.
It can enhance the physiological metabolism of cells, promote blood circulation, enhance the metabolism of animal bodies, and play a nutritional and health role. Research has shown that it can promote the growth of bifidobacteria and lactic acid bacteria, and has the effect of probiotics.
5. Astragaloside IV can improve cardiovascular function.
Strengthen cardiac contractility, protect myocardium, and combat heart failure. It also has liver protection, anti-inflammatory, analgesic and other effects. It can be used as an adjuvant therapy for various viral and bacterial diseases.
